Generated by All in One SEO v4.9.7.2, this is an llms.txt file, used by LLMs to index the site. # HELP Helminth Elimination Platform ## Sitemaps - [XML Sitemap](https://eliminateworms.org/sitemap.xml): Contains all public & indexable URLs for this website. ## Posts - [News](https://eliminateworms.org/news/) - [The long and winding road towards new treatments against lymphatic filariasis and onchocerciasis](https://eliminateworms.org/2024/the-long-and-winding-road-towards-new-treatments-against-lymphatic-filariasis-and-onchocerciasis/) - by Risch F, Kazakov A, Specht S, Pfarr K, Fischer PU, Hoerauf A, Hübner MP. Trends in Parasitology 2024. doi: 10.1016/j.pt.2024.07.005 1 Although lymphatic filariasis and onchocerciasis have been targeted for global elimination, these helminth infections are still a major public health problem across the tropics and subtropics. Despite decades of research, treatment options remain limited; drugs that - [Empowering Tanzanian journalists and researchers in science communication](https://eliminateworms.org/2024/integrating-science-journalism-workshop/) - On 20 February 2024, journalists and researchers joined a three-day communication workshop organized by the Ifakara Health Institute and DNDi, and conducted by SciDev, in Bagamoyo, Tanzania as part of the Helminth Elimination Platform (HELP) consortium. The media workshop was held to improve journalists’ and health reporters’ skills in reporting on neglected tropical diseases (NTDs) - [Flussblindheit: Die tückische Infektionskrankheit, die Menschen das Augenlicht raubt](https://eliminateworms.org/2022/flussblindheit-die-tuckische-infektionskrankheit-die-menschen-das-augenlicht-raubt/) - River blindness: The insidious infectious disease that blinds people An article on river blindness in the Democratic Republic of Congo published in GEO. Read article - [‘Out of sight’: DNDi's work on river blindness featured in German magazine GEO](https://eliminateworms.org/2022/out-of-sight-dndi-work-on-river-blindness-featured-in-german-magazine-geo/) - The GEO reporters follow Sabine Specht, DNDi’s Head of Filarial Diseases, and a team of Congolese researchers and doctors, from the fishing villages along the Onane river in the rainforest – where they visited patients and local health workers – to the Masi-Manimba hospital almost 2,000 kilometers away in the western DRC, where DNDi is conducting - [Tropenkrankheiten: „Auf diese Weise werden Armutskreisläufe kreiert“](https://eliminateworms.org/2022/tropenkrankheiten-auf-diese-weise-werden-armutskreislaufe-kreiert/) - Tropical diseases: "This is how poverty cycles are created" An interview of Dr Sabine Specht, DNDi, published by Frankfurter Rundschau. Read article - [Public-private partnership launched to develop new drugs for roundworm infections](https://eliminateworms.org/2019/public-private-partnership-launched-to-develop-new-drugs-for-roundworm-infections/) - Geneva – 28 November 2019 “Pan-nematode” drug development platform is part of Europe’s Horizon 2020 programme A new consortium of research institutes, universities, not-for-profit organizations, and pharmaceutical companies has teamed up to develop novel drugs for infections caused by parasitic worms (helminths), a debilitating group of diseases that includes river blindness, lymphatic filariasis, as well - [Vernachlässigte Tropenkrankheiten - es trifft immer die Armen](https://eliminateworms.org/2021/vernachlassigte-tropenkrankheiten-es-trifft-immer-die-armen/) - "Neglected tropical diseases - it always hits the poor" Deutsche Welle article on neglected tropical diseases profiling the work of the HELP consortium to develop new filarial disease treatments. Read article - [New treatment for human parasitic worm infections shows high efficacy](https://eliminateworms.org/2023/new-treatment-for-human-parasitic-worm-infections-shows-high-efficacy/) - A new drug candidate shows promising results in treating parasitic worm infections. Researchers at Swiss TPH tested efficacy and safety of emodepside against the three most important soil-transmitted helminths on Pemba Island in Tanzania. Emodepside is the first new promising drug against parasitic worm infections since several decades. Swiss TPH will now join forces with - [Investing in new drugs to combat parasitic worm infections](https://eliminateworms.org/2023/investing-in-new-drugs-to-combat-parasitic-worm-infections/) - An article published by Jennifer Keiser, Associate Professor and Head of Helminth Drug Development, Swiss Tropical and Public Health Institute (Swiss TPH) in The Guardian. Read more - [University Hospital Bonn coordinates eWHORM project to combat worm infections in sub-Saharan Africa](https://eliminateworms.org/2023/university-hospital-bonn-coordinates-ewhorm-project-to-combat-worm-infections-in-sub-saharan-africa/) - African and European partners join forces to enable the World Health Organisation's "Roadmap for Neglected Tropical Diseases" and reduce the burden of disease associated with worm infections. Read more - [Current recommended treatment against whipworm shows better results than new drug combination](https://eliminateworms.org/2022/current-recommended-treatment-against-whipworm-shows-better-results-than-new-drug-combination/) - Swiss TPH researchers tested two different drug combinations against the parasitic worm Trichuris trichiura on Pemba Island, Tanzania. Findings show that a new treatment combination (moxidectin and albendazole) is inferior compared to the current recommended treatment combination (ivermectin and albendazole). However, moxidectin might serve as an alternative in areas in which ivermectin is not readily - [Prof. Dr. Achim Hörauf (IMMIP, UK Bonn): Antibiotikum gegen Wurminfektionen](https://eliminateworms.org/2022/achim-horauf-antibiotikum-gegen-wurminfektionen/) - Prof. Dr Achim Hörauf (IMMIP, UK Bonn): Antibiotic against worm infections - [Improving treatment of helminth infections](https://eliminateworms.org/2021/improving-treatment-of-helminth-infections/) - An article published by Swiss TPH. Read article - [Support für frühe Arzneimittelstudie des Swiss TPH](https://eliminateworms.org/2021/support-fur-fruhe-arzneimittelstudie-des-swiss-tph/) - "Support for early drug development study by Swiss TPH" An article published by the Department of Clinical Research of the University of Basel. Read article - [Could veterinary drug candidates work against human parasitic infections?](https://eliminateworms.org/2021/could-veterinary-drug-candidates-work-against-human-parasitic-infections/) - An article published by Elanco. Read article - [Promising treatment alternative against parasitic worm infection](https://eliminateworms.org/2021/promising-treatment-alternative-against-parasitic-worm-infection/) - Strongyloidiasis, a parasitic worm infection caused by soil-transmitted helminths, remains a neglected public health problem with limited treatment options. Swiss TPH researchers conducted the first dose-finding study with moxidectin against strongyloidiasis. The drug could become a treatment alternative to the only treatment available so far and help fill the empty anthelminthic drug pipeline. Read more - [Artificial intelligence in the fight against river blindness](https://eliminateworms.org/2020/artificial-intelligence-in-the-fight-against-river-blindness/) - A news shared by The Institute for Medical Microbiology, Immunology and Parasitology at the Universitätsklinikum Bonn. Read more - [The design and development of a multicentric protocol investigating the impact of doxycycline on lymphodema](https://eliminateworms.org/2020/the-design-and-development-of-a-multicentric-protocol-investigating-the-impact-of-doxycycline-on-lymphodema/) - A news shared by The Institute for Medical Microbiology, Immunology and Parasitology at the Universitätsklinikum Bonn. Read more ## Pages - [Developing new drugs for infections caused by parasitic worms](https://eliminateworms.org/) - Helminth diseases are a debilitating group of diseases that are caused by parasitic worms and include river blindness (onchocerciasis), lymphatic filariasis, as well as infection with roundworm, hookworm, and whipworm (soil-transmitted helminths). Together these diseases affect close to one billion people. Current treatments all present limitations. The current approach to eliminating helminth diseases is based - [Scientific articles](https://eliminateworms.org/scientific-articles/) - Scientific articles on the HELP Consortium project Repurposing oxfendazole for onchocerciasis: Population pharmacokinetics of a tablet formulation in healthy African adults by Assmus F, Adehin A, Hoglund RM, Nyaulingo G, Mbarak H, Jongo S, Ackermann E, Reus E, Keiser J, Barreira Da Silva Rocha F, Specht S, Scandale I, Tarning J. CPT: Pharmacometrics & Systems - [Events](https://eliminateworms.org/events/) - 2024 TEDxGVAGrad 20 April 2024 | Geneva, Switzerland Sabine Specht, DNDi, TEDxTalk 'The sight-stealing worm: Searching for a cure for river blindness' Watch the TEDx Talk British Society for Parasitology Spring Meeting 2-5 April 2024 | Liverpool, UK Sabine Specht, DNDi, keynote presentation 'Development of alternative treatments for filarial diseases' Workshop on integrating science and - [River blindness (Onchocerciasis)](https://eliminateworms.org/diseases/river-blindness/) - About the disease Filarial diseases are a debilitating group of diseases caused by parasitic worms transmitted by the bite of blood-feeding insects. People are infected with river blindness (also known as onchocerciasis) by repeated exposure to blackflies infected with Onchocerca volvulus worms and breeding in fast-flowing rivers. River blindness is not usually fatal, but it inflicts hardship and misery on millions - [About us](https://eliminateworms.org/about-us/) - Collaboration for innovation: Establishment of a pan-nematode drug development platform The Helminth Elimination Platform (HELP) is a consortium of research institutes, universities, not-for-profit organizations, and pharmaceutical companies, formed in 2019 to develop new drugs for infections caused by parasitic worms (helminths). The consortium is focusing on soil-transmitted helminthiases and river blindness (onchocerciasis), since these infections are among - [Diseases](https://eliminateworms.org/diseases/) - Helminth diseases are a debilitating group of diseases that are caused by parasitic worms and include river blindness (onchocerciasis), lymphatic filariasis, as well as infection with roundworm, hookworm, and whipworm (soil-transmitted helminths). Together these diseases affect close to one billion people. Read about river blindness Read about soil-transmitted helminths - [Soil-transmitted helminthiasis](https://eliminateworms.org/diseases/soil-transmitted-helminthiasis/) - About the disease Parasitic worm infections are a major public health issue in many tropical and subtropical low- and middle-income countries. Among the leading neglected tropical diseases are soil-transmitted helminth infections or soil-transmitted helminthiasis (STH), which are caused by infections with three types of helminths, including the large roundworm Ascaris lumbricoides, the hookworms Necator americanus ## My Templates - [Scientific Articles category](https://eliminateworms.org/?elementor_library=scientific-articles-category) - Scientific articles on the HELP Consortium project The long and winding road towards new treatments against lymphatic filariasis and onchocerciasis 8 August 2024 by Risch F, Kazakov A, Specht S, Pfarr K, Fischer PU, Hoerauf A, Hübner MP. Trends in Parasitology 2024. doi: 10.1016/j.pt.2024.07.005 1 Although lymphatic filariasis and onchocerciasis have been targeted for global elimination, these helminth - [Default Kit](https://eliminateworms.org/?elementor_library=default-kit) ## Categories - [News](https://eliminateworms.org/category/news/) ## Tags - [IN THE MEDIA](https://eliminateworms.org/tag/in-the-media/) - [PRESS RELEASES](https://eliminateworms.org/tag/press-releases/)